| Gastric carcinoids are rare tumours. Clinical setting: - Type I - Associated with chronic atrophic gastritis with or without pernicious anemia. In autoimmune gastritis progressive destruction of the specialised parietal and chief cell zone leads to atrophy , intestinal metaplasia , hypochlorhydria and hypergastrinemia. - Type II - In Zollinger Ellison syndrome, particularly in patients associated with multiple endocrine neoplasia type 1. - Type III - Sporadic tumours - Not related to hypergastrinemia - In the antrum or corpus - Larger lesion, may be ulcerated. - May have an aggressive course. |
Sunday, December 5, 2010
Classification of Gastric Carcinoid tumors
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