Anti fungal therapies

Amphotericin B
Azoles: block Ergosterol synthesis which is an component of fungal cell wall
Echinocandins: Inhibit glucan synthase which is specific for fungal wall (eg: caspofungin)

Link

Colitis Cystica Profunda

http://www.ajronline.org/cgi/reprint/131/3/529.pdf

Laparoscopic Abdominal Wall Reconstruction

Movie link

Definition of hypersplenism

- Splenomegaly
- cytopenia(s) - usually thrombocytopenia, anemia or neutropenia
- normal or hyperplastic bone marrow
- response to splenectomy

Meckler's Triad

http://www.ncbi.nlm.nih.gov/pubmed/20935623

GAIL model for breast cancer risk assessment

http://www.cancer.gov/bcrisktool/

- age
- age of menses
- age of first child
- first degree relative with breast cancer
- previous breast biopsies
- History of ADH
- race

Sent from iPhone

Drugs that cause acute pancreatitis

"DEFEATS"

D: didanosine (anti-HIV drug)
E: erthyromycin
F: furosemide
E: estrogens
A: azithromycin (Imuran)
T: tetracycline
S: sulfa

Drugs Associated with Pancreatitis:

Definite Cause
·       5-Aminosalicylate ·       6-Mercaptopurine ·       Azathioprine ·       Cytosine arabinoside ·       Dideoxyinosine ·       Diuretics ·       Estrogens ·       Furosemide	·       Metronidazole ·       Pentamidine ·       Tetracycline ·       Thiazide ·       Trimethoprim-sulfamethoxide ·       Valproic acid
Probable Cause
·       Acetaminophen ·       α-Methyl-DOPA ·       Isoniazid ·       L-Asparaginase	·       Phenformin ·       Procainamide ·       Sulindac