Phyllodes Tumor

·      Varying malignant potential

·      Round, may be indistinguishable from fibroadenoma

·      Comprised of epithelial elements and connective tissue stroma (like a fibroadenoma)

Classification:

·      Benign

·      Borderline

·      Malignant

·      Based on cellular atypia

·      Mitotic activity

·      Overgorwth in stroma

·      Phyllodes tumors have increased cellular activity compared to fibroadenomas

·      If malignant treat with adjuvant therapy like a sarcoma

Treatment:

·      Excise with a 1 cm margin of normal breast tissue

·      Re-excision is often necessary to achieve this margin

·      LN dissection is not necessary

·      LN mets <5% of cases

·      If LN mets to axilla then pt has a very poor prognosis