Lugol's iodine (KI)
- short term antithyroid medication
- inhibits thyroglobulin proteolysis (which prevents release of T4/3)
- also prevents organification of thyroid hormone
- effects last 10-14 days
T3 production inhibitors
- major role of beta-blockers is to block the peripheral conversion of T4 to T3
- they do this in addition to treat symptomatic effects of hyperthyroidism.
Radioactive iodine.
- 131I
- trapped by follicular cells incorporated into tyrosine complex and deposited into colloid where beta dray destroys surrounding parenchyma
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