Doxorubicin

Aka: Adriamycin

Anthracycline based chemotherapeutic used for variety of cancers including breast cancer and sarcomas.
- Intercalates with DNA and is non-cell cycle specific.

Rate limiting toxicity is myelosuppression and cardiotoxicity.
- Cardiotoxicity usually presents as chronic cardiomyopathy after prolonged use.  Acute cardiac arrythmias are rare