Aka: Taxol
Plant based taxane molecule used for breast cancer. Also used in lung, H&N ca.
- binds tubules of cells and prevents rapidly proliferating cells from replicating
Myelosuppression (neutropenia) predominates and is usually dose-limiting.
Other common less severe SE:
- mucositis, peripheral neuropathy, cardiac SE (HTN, hypotn, arrythmias), alopecia
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